Tag. Fort-building. Skipping. CUVITRU® is for kids too.

CUVITRU is approved for use as replacement therapy for PI in pediatric patients ≥2 years.

Get a better understanding of how CUVITRU can help treat your child with PI.

2 years and older icon.

CUVITRU [Immune Globulin Subcutaneous (Human)] 20% is approved for the treatment of PI in people 2 years and older. When your child is diagnosed with PI, there are questions, worries, and uncertainties. Understanding your child’s PI and managing it with treatment that can be tailored to meet your child’s individual infusion needs can make a difference.1,2

Kids in the clinical study had reliable protection from infection and consistent IG levels.1

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In the North American (NA) clinical study of CUVITRU, in both adult and pediatric patients:

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Less than 1 serious bacterial infection

On average, people taking CUVITRU experienced 0.012 acute serious bacterial infections (ASBIs), which is significantly less than 1*

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Less than 3 serious infections of any kind

The rate of any kind of infection was 2.41

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About a day missed of work or school

The amount of time people taking CUVITRU were unable to attend work/school or perform normal daily activities due to illness or infection1

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No ASBIs were experienced by kids taking CUVITRU

In the NA clinical study, no pediatric patients experienced an ASBI*

*One ASBI that occurred during the study was a case of pneumonia in a 78-year-old subject who had specific antibody deficiency.

CUVITRU was studied in 77 adult and pediatric patients with PI >2 years of age in North America. Efficacy—that is, if an immunoglobulin treatment works—was determined in 53 adults aged 16 years or older, 6 adolescents aged 12 to <16 years, and 15 children aged 2 to <12 years. The main goal of the study was to measure how many acute serious bacterial infections (ASBIs) were experienced over the course of 1 year. The FDA standard for efficacy is 1 ASBI per year. ASBIs were evaluated in 74 people taking CUVITRU for an average of 380.5 days (range, 3-629 days).1

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Caregiver Brochure

We’ve created a brochure for caregivers about PI and its treatment with CUVITRU. It’s packed full of helpful information designed to boost your confidence about helping your child with treatment.

With CUVITRU, your child could infuse every 2 weeks.

How can CUVITRU fit into your child’s life?

The length and frequency of infusions will depend on your child’s prescribed dose, the way they respond to treatment, and their individual needs. Their doctor will work with you to customize their administration plan to best suit your family’s lifestyle. Below, you’ll find a few examples of sample treatment plans—so you can get an idea of what others’ treatments are like.*

14-year-old CUVITRU patient, Sam.
12-gram dosage icon.

60-mL dose

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Infused every 
2 weeks

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60 mL/hour/site
in 2 sites

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Infusion time
~30 minutes

Sam      14 years, 106 lb

10-year-old CUVITRU patient, Alexie.
8-gram dosage icon.

40-mL dose

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Infused every 
2 weeks

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45 mL/hour/site
in 1 site

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Infusion time
just under an

3-year-old CUVITRU patient, George.
3-gram dosage icon.

15-mL dose

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One infusion-site location on light blue body icon.

30 mL/hour/site
in 1 site

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Infusion time 
~30 minutes

George  3 years, 31 lb

*Results represent examples of patients' experiences. Individual results may vary. Images depicted are not actual patients.

Doctor Discussion Guide PDF.

Doctor Discussion Guide

Talk to your child’s doctor to see if CUVITRU is right for them. We have a Doctor Discussion Guide that you can fill out for your child to answer questions about infusion concerns and preferences that might be a helpful starting place for a conversation.

Hadlie Jo has more time for dance practice.

Before CUVITRU, Hadlie Jo was on a weekly treatment that took her 2.5 hours to infuse. With CUVITRU, she infuses for less than an hour every other week*—and that gives her the time to live a more active life.

*Results represent an example patient experience. Individual results may vary.

With training, you can give your child their infusion at home.

If you and your child’s doctor decide that CUVITRU is right for them, you’ll receive in-person training for at-home administration, as well as a detailed step-by-step guide. The guide will help you as you learn to administer CUVITRU to your child on your own. It may feel unfamiliar at first, but you’ll become experienced with practice.

Do not use CUVITRU at home until you get nurse training on how to infuse.

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The infusion process is broken down into 4 sections.

Our goal is that you feel confident in your ability to complete your child’s infusion in the comfort of your home.


Get organized


Prep and draw


Start infusion


Remove needle(s)
and wrap up

Turn infusion time into a positive.

Keeping disruptions to a minimum is very important during infusions. To establish infusion time as a routine and reduce potential stress, create an “infusion zone” that helps your child feel more comfortable during infusions. You can set up your child’s infusion zone however you wish, but here are some suggestions:

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Consider using sensory distraction techniques

Some examples include a buzzing toy or a smooth rock that the child can paint and keep in the freezer. Your child can hold the sensory toy or cold rock for comfort and to feel involved in their treatment. You can even decorate your own “comfort item” with your child to remind them that you’re there for them during their infusions.

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A toy, book, smartphone, or laptop game

These might help your child stay calm, still, and distracted from needles or pain. These simple, everyday objects can help keep your child’s mind occupied and divert their attention from the infusion experience.

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If you feel it’s appropriate, involve siblings in the process

They may feel like the child with PI is receiving all the attention, so getting them involved could help avoid hurt feelings.

What are some possible common side effects of CUVITRU?

After their CUVITRU infusion, your child may experience one or more possible side effects. These effects generally go away within a few hours and are less likely to occur after their first few infusions.

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Local side effects can include:

Mild or moderate pain, redness, and itching

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Systemic side effects can include:

Headache, fatigue, vomiting, nausea, and diarrhea

Contact your HCP if any of these side effects bother your child or don’t go away.

It can help to read the stories of real PI patients doing what they love.

With their doctors, each patient created a treatment plan with CUVITRU that is tailored to their needs.

Hadlie Jo.
Ambassador Julie.
Ambassador Walter.


1. CUVITRU. Prescribing Information, Takeda Pharmaceuticals USA Inc.; 2023.

2. Data on file. Takeda US Inc. 2015.