Starting Patients

Information for starting your patients on CUVITRU

Once a treatment decision has been made, there are different options for getting your patients started on treatment:

The information provided below can help ensure your patients are equipped with everything they need for an optimal administration experience. 

CUVITRU is supplied in single-use vials

CUVITRU is supplied in single-use vials containing the labeled amount of functionally active IgG. The components used in the packaging for CUVITRU are not made with natural rubber latex.1

The following presentations of CUVITRU are available:

NDC NumberVOLUME
0944-2850-015 mL
0944-2850-0310 mL
0944-2850-0520 mL
0944-2850-0740 mL
0944-2850-0950 mL
NDC NumberGRAMS PROTEIN
0944-2850-011.0
0944-2850-032.0
0944-2850-054.0
0944-2850-078.0
0944-2850-0910.0
NDC NumberVOLUMEGRAMS PROTEIN
0944-2850-015 mL1.0
0944-2850-0310 mL2.0
0944-2850-0520 mL4.0
0944-2850-0740 mL8.0
0944-2850-0950 mL10.0

Storage and handling1

Thermometer icon.
  • Store at refrigeration temperature: 2°C to 8°C
    [36°F to 46°F] for up to 36 months OR room temperature: not to exceed 25°C [77°F] for up to 24 months
  • Do not return CUVITRU to the refrigerator if you take it out to room temperature 
  • Do not freeze
Exclamation point icon.
  • Do not shake
  • Keep the vials in the carton in order to protect from light
  • Discard any unused product
  • Do not use past the expiration date

Achieving an optimal administration experience requires appropriate supplies1

The following information is intended to assist HCPs in selection of appropriate equipment in order to achieve the maximum infusion rate of 60 mL/h/site with CUVITRU. Takeda does not prefer, recommend, or attest to using any specific infusion pump or other ancillary devices. For the first two infusions of CUVITRU, the recommended infusion rate is 10-20 mL/hr/site. For subsequent infusions, the infusion rate may be increased to 60 mL/hr/site as tolerated (e.g., 60 mL/hr/site x 2 sites = 120 mL/hr).

Follow each infusion pump’s manufacturer guidelines before use and administration.

  • RMS Freedom Infusion System2,3

  • Freedom60® Pump
      • Precision™ Flow Rate Tubing:
      • F180
      • Infusion Rate (1 site):
      • 11.59 mL/hr
      • Infusion Rate (2 sites):
      • 6.00 mL/hr
      • Precision™ Flow Rate Tubing:
      • F275
      • Infusion Rate (1 site):
      • 17.07 mL/hr
      • Infusion Rate (2 sites):
      • 8.99 mL/hr
      • Precision™ Flow Rate Tubing:
      • F500
      • Infusion Rate (1 site):
      • 28.63 mL/hr
      • Infusion Rate (2 sites):
      • 15.66 mL/hr
      • Precision™ Flow Rate Tubing:
      • F600
      • Infusion Rate (1 site):
      • 33.21 mL/hr
      • Infusion Rate (2 sites):
      • 18.45 mL/hr
      • Precision™ Flow Rate Tubing:
      • F900
      • Infusion Rate (1 site):
      • 45.28 mL/hr
      • Infusion Rate (2 sites):
      • 26.20 mL/hr
      • Precision™ Flow Rate Tubing:
      • F1200
      • Infusion Rate (1 site):
      • 55.34 mL/hr
      • Infusion Rate (2 sites):
      • 33.19 mL/hr
      • Precision™ Flow Rate Tubing:
      • F2400
      • Infusion Rate (1 site):
      • N/A
      • Infusion Rate (2 sites):
      • 55.27 mL/hr
    • High-Flo Subcutaneous Safety Needle Sets™

    • 24 g high-flow needle sets
  • EMED SCiG Infusion System4,5

  • SCIg60 Infuser™ Pump
      • Infuset™ Flow Rate Tubing:
      • Infuset™ 190
      • Infusion Rate (1 site):
      • 11.59 mL/hr
      • Infusion Rate (2 sites):
      • 6.00 mL/hr
      • Infuset™ Flow Rate Tubing:
      • Infuset™ 290
      • Infusion Rate (1 site):
      • 17.07 mL/hr
      • Infusion Rate (2 sites):
      • 8.99 mL/hr
      • Infuset™ Flow Rate Tubing:
      • Infuset™ 430
      • Infusion Rate (1 site):
      • 28.63 mL/hr
      • Infusion Rate (2 sites):
      • 15.66 mL/hr
      • Infuset™ Flow Rate Tubing:
      • Infuset™ 650
      • Infusion Rate (1 site):
      • 33.21 mL/hr
      • Infusion Rate (2 sites):
      • 18.45 mL/hr
      • Infuset™ Flow Rate Tubing:
      • Infuset™ 820
      • Infusion Rate (1 site):
      • 45.28 mL/hr
      • Infusion Rate (2 sites):
      • 26.20 mL/hr
      • Infuset™ Flow Rate Tubing:
      • Infuset 930
      • Infusion Rate (1 site):
      • 55.34 mL/hr
      • Infusion Rate (2 sites):
      • 33.19 mL/hr
      • Infuset™ Flow Rate Tubing:
      • Infuset 1850
      • Infusion Rate (1 site):
      • N/A
      • Infusion Rate (2 sites):
      • 55.27 mL/hr
    • Soft-Glide™ Needle Sets

    • 24 g high-flow needle sets

Working with your specialty pharmacy provider

When getting started on therapy, your patients will receive CUVITRU from a specialty pharmacy provider (SPP). Here are some considerations when working with an SPP:

  • Is CUVITRU covered under the pharmacy or medical benefit? This will impact how your office acquires CUVITRU and is reimbursed 
  • Check the patient’s health plan to see which SPPs are covered (see authorized list below)
  • Avoid substitution by having the healthcare provider specify “dispense as written” (DAW) on the CUVITRU prescription
  • If the SPP form doesn’t have CUVITRU listed, clearly write it on the form
  • Confirm that the appropriate tubing, ancillaries, and/or accompanying medications are dispensed alongside CUVITRU 

Find an authorized CUVITRU SPP

Patient’s prescribed CUVITRU may receive it from an SPP. Check your patient’s insurance coverage to determine which SPP is within your patient’s network.

Printable version of SPP providers available

Review safety information

Review Important Safety Information, including contraindications and other specific warnings and precautions to consider when prescribing and monitoring patients treated with CUVITRU.

Comparable coverage to other PI treatments

Coverage requirements for CUVITRU may vary by plan. Take advantage of the insurance resources available to help your patients get timely access to CUVITRU.