CUVITRU is indicated as replacement therapy for primary humoral immunodeficiency (PI) in adult and pediatric patients ≥2 years. CUVITRU is for subcutaneous use only.

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Help give your patients
the administration
experience they want.

INFUSION CALCULATOR &
ANCILLARY SUPPPLIES

Explore administration combinations and supplies

Use the infusion calculator to explore CUVITRU [Immune Globulin Subcutaneous (Human)] 20% Solution administration parameter combinations for your patients based on needlesticks and frequency of infusions, and help your patients achieve CUVITRU’s maximum infusion rate by selecting the proper supplies.


Needlesticks & infusion time calculator*1

Get started

*CUVITRU: Maximum volume per site is 60 mL/site as tolerated (except for the first 2 infusions for patients <40 kg). Maximum infusion rate is 60 mL/hr/site as tolerated (after first 2 infusions). Up to 4 sites simultaneously may be used.1

Calculations are based on a 28-day month and assumes the maximum volume per site and maximum infusion rate after the first two infusions.

All values are rounded up to the nearest whole number. This tool does not provide treatment recommendations or infusion parameters.

Choose a monthly SCIG 20% dose

16 g
32 g
40 g
48 g
64 g
80 g

*CUVITRU: Maximum volume per site is 60 mL/site as tolerated (except for the first 2 infusions for patients <40 kg). Maximum infusion rate is 60 mL/hr/site as tolerated (after first 2 infusions). Up to 4 sites simultaneously may be used.1

Calculations are based on a 28-day month and assumes the maximum volume per site and maximum infusion rate after the first two infusions.

All values are rounded up to the nearest whole number. This tool does not provide treatment recommendations or infusion parameters.

Choose the desired infusion frequency

Daily
Weekly
Every 10 days
Every 2 weeks

*CUVITRU: Maximum volume per site is 60 mL/site as tolerated (except for the first 2 infusions for patients <40 kg). Maximum infusion rate is 60 mL/hr/site as tolerated (after first 2 infusions). Up to 4 sites simultaneously may be used.1

Calculations are based on a 28-day month and assumes the maximum volume per site and maximum infusion rate after the first two infusions.

All values are rounded up to the nearest whole number. This tool does not provide treatment recommendations or infusion parameters.

Results

Monthly dose
SCIG 20%
Dosing schedule
Needlesticks
1
2
3
4
Infusion time
minutes
minutes
minutes
minutes
Total volume per
SCIG 20% infusion:
mL

*CUVITRU: Maximum volume per site is 60 mL/site as tolerated (except for the first 2 infusions for patients <40 kg). Maximum infusion rate is 60 mL/hr/site as tolerated (after first 2 infusions). Up to 4 sites simultaneously may be used.1

Calculations are based on a 28-day month and assumes the maximum volume per site and maximum infusion rate after the first two infusions.

All values are rounded up to the nearest whole number. This tool does not provide treatment recommendations or infusion parameters.

Review Important Safety Information, including adverse reactions.

Achieving an optimal experience requires appropriate supplies1

The following information is intended to assist HCPs in selection of appropriate equipment in order to achieve the maximum infusion rate of 60 mL/h/site with CUVITRU. Takeda does not prefer, recommend, or attest to using any specific infusion pump or other ancillary devices.

Follow each infusion pump’s manufacturer guidelines before use and administration.

    • RMS Freedom
      Infusion
      System2,3

    • Freedom60® Pump
        • Precision™ Flow
          Rate Tubing:
        • F180
        • Infusion Rate
          (1 site):
        • 11.59
          mL/hr
        • Infusion Rate
          (2 sites):
        • 6.00
          mL/hr
        • Precision™ Flow
          Rate Tubing:
        • F275
        • Infusion Rate
          (1 site):
        • 17.07
          mL/hr
        • Infusion Rate
          (2 sites):
        • 8.99
          mL/hr
        • Precision™ Flow
          Rate Tubing:
        • F500
        • Infusion Rate
          (1 site):
        • 28.63
          mL/hr
        • Infusion Rate
          (2 sites):
        • 15.66
          mL/hr
        • Precision™ Flow
          Rate Tubing:
        • F600
        • Infusion Rate
          (1 site):
        • 33.21
          mL/hr
        • Infusion Rate
          (2 sites):
        • 18.45
          mL/hr
        • Precision™ Flow
          Rate Tubing:
        • F900
        • Infusion Rate
          (1 site):
        • 45.28
          mL/hr
        • Infusion Rate
          (2 sites):
        • 26.20
          mL/hr

    • EMED SCiG
      Infusion
      System4,5

    • SCIg60 Infuser™ Pump
        • Infuset™ Flow
          Rate Tubing:
        • Infuset™
          190
        • Infusion Rate
          (1 site):
        • 11.59
          mL/hr
        • Infusion Rate
          (2 sites):
        • 6.00
          mL/hr
        • Infuset™ Flow
          Rate Tubing:
        • Infuset™
          290
        • Infusion Rate
          (1 site):
        • 17.07
          mL/hr
        • Infusion Rate
          (2 sites):
        • 8.99
          mL/hr
        • Infuset™ Flow
          Rate Tubing:
        • Infuset™
          430
        • Infusion Rate
          (1 site):
        • 28.63
          mL/hr
        • Infusion Rate
          (2 sites):
        • 15.66
          mL/hr
        • Infuset™ Flow
          Rate Tubing:
        • Infuset™
          650
        • Infusion Rate
          (1 site):
        • 33.21
          mL/hr
        • Infusion Rate
          (2 sites):
        • 18.45
          mL/hr
        • Infuset™ Flow
          Rate Tubing:
        • Infuset™
          820
        • Infusion Rate
          (1 site):
        • 45.28
          mL/hr
        • Infusion Rate
          (2 sites):
        • 26.20
          mL/hr
Use to achieve the maximum flow rate of 60 mL/hr/site
        • Precision™ Flow
          Rate Tubing:
        • F1200
        • Infusion Rate
          (1 site):
        • 55.34
          mL/hr
        • Infusion Rate
          (2 sites):
        • 33.19
          mL/hr
        • Precision™ Flow
          Rate Tubing:
        • F2400
        • Infusion Rate
          (1 site):
        • N/A
        • Infusion Rate
          (2 sites):
        • 55.27
          mL/hr

      • HIgH-Flo Subcutaneous
        Safety
        Needle Sets™

      • 24 g high-flow
        needle sets
        • Infuset™ Flow
          Rate Tubing:
        • Infuset™
          930
        • Infusion Rate
          (1 site):
        • 55.34
          mL/hr
        • Infusion Rate
          (2 sites):
        • 33.19
          mL/hr
        • Infuset™ Flow
          Rate Tubing:
        • Infuset™
          1850
        • Infusion Rate
          (1 site):
        • N/A
        • Infusion Rate
          (2 sites):
        • 55.27
          mL/hr

      • Soft-Glide™
        Needle Sets

      • 24 g high-flow
        needle sets

Cuvitru Safety Information

There are known risk factors to consider with Cuvitru. Review the full safety information, including contraindications and specific warnings and precautions to take when monitoring patients with Cuvitru.

For more information, contact a Takeda representative.

Contact a Rep
  1. CUVITRU [Prescribing Information]. Lexington, MA: Baxalta US Inc.
  2. US Food and Drug Administration. 501(K) Premarket Notification. Integrated Catch-Up Freedom Syringe Driver Infusion System. Published August 31,
    2017. Accessed Septemer 27, 2019.
  3. RMS Medical Products. Freedom60 Syringe Infusion System: Instructions for Use. Chester, NY: RMS Medical Products; 2017.
  4. US Food and Drug Administration. 501(K) Premarket Notification K173738. SCIg60 Infusion System. Published December 14, 2018. Accessed September 27, 2019.
  5. Integrated Medical Systems, Inc. EMED SCIg60 Infusion System Manual. Alsip, IL: EMED Technologies; 2018.

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